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monocytes

Comparison of the Cytokine Profile in Mesenchymal Stem Cells from Human Adipose, Umbilical Cord, and Placental Tissues

[Cellular Reprogramming] MSCs were extracted from adipose, umbilical cord, and placental tissues. The expression levels of 80 cytokines were detected, and the data demonstrated that the three MSC types abundantly secreted insulin-like growth factor-binding protein (IGFBP)-4, IGFBP-3, tissue inhibitor of metalloproteinase (TIMP)-1, TIMP-2, IGFBP-6, monocyte chemoattractant protein-1, and granulocyte colony-stimulating factor.

CD200 Expression in Hematopoietic Neoplasms: Beyond a Marker for Diagnosis of B Cell Neoplasms

[Critical Reviews in Oncology Hematology] Investigators review CD200 expression and its role in the immune evasion of non-B cell hematopoietic neoplasms and conclude that CD200 appears to be involved in the immune evasion of malignant cells, which could affect the survival of patients.

Adoptive Cell Therapy with Tumor-Specific Th9 Cells Induces Viral Mimicry to Eliminate Antigen-Loss-Variant Tumor Cells

[Cancer Cell] Researchers demonstrated that murine and human T helper (Th) 9 cells, but not Th1/Tc1 or Th17 cells, expressing tumor-specific T cell receptors or CARs, eradicated advanced tumors that contained antigen-loss-variant.

Innate Immune Responses at the Asymptomatic Stage of Influenza a Viral Infections of Streptococcus pneumoniae Colonized and Non-Colonized Mice

[Scientific Reports] Researchers compared innate immune responses in the lungs of healthy colonized and non-colonized mice after Influenza A virus challenge at the initial asymptomatic stage of infection.

The Epithelial-Stromal Microenvironment in Early Colonic Neoplasia

[Molecular Cancer Research] Scientists analyzed molecular changes within the epithelial and stromal compartments of dysplastic aberrant crypt foci formed in the ascending colon, where rapidly developing interval cancers occur.

Single-Cell RNA Sequencing Reveals Distinct Tumor Microenvironmental Patterns in Lung Adenocarcinoma

[Oncogene] To identify clinically relevant microenvironmental and cancer features, scientists applied single-cell RNA sequencing to ten human lung adenocarcinomas and ten normal control tissues.

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