myeloid cells

[Nature Communications] Researchers showed a Pf ‘decision-sensing-system’ controlled by CXCL10 concentration. High CXCL10 expression prompted P. falciparum to initiate a survival strategy via growth acceleration.

[Scientific Reports] Scientists investigated the effect of diesel exhaust particles (DEP) exposure on allergic rhinitis using a mouse model. BALB/c mice sensitized to house dust mite (HDM) were intranasally challenged with HDM in the presence and absence of DEP.

[Scientific Reports] To investigate the mechanism of cysteine protease cathepsin S (CTSS) in systemic lupus erythematosus (SLE), CTSS-overexpressing transgenic mice were generated, and induced lupus-like symptoms.

[Proceedings of the National Academy of Sciences of the United States of America] In vitro studies demonstrated that IFP35 and NMI were released by multiple cells. IFP35 and NMI subsequently triggered nuclear factor kappa B–dependent activation of microglia via the TLR4 pathway.

[Heliyon] Scientists investigated the effects of Orengedokuto on inflammatory molecule induction in BV-2 microglial cells using real-time RT-PCR and ELISA.

[Nature Communications] Scientists showed that the deubiquitinase USP12 was commonly downregulated in the KrasG12D-driven mouse lung tumour and human non-small cell lung cancer owing to the activation of AKT-mTOR signalling.