Malaria Parasites Both Repress Host CXCL10 and Use It as a Cue for Growth Acceleration

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Justin.choi
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Researchers showed a Pf ‘decision-sensing-system’ controlled by CXCL10 concentration. High CXCL10 expression prompted P. falciparum to initiate a survival strategy via growth acceleration.
[Nature Communications]
Ofir-Birin, Y., Ben Ami Pilo, H., Cruz Camacho, A., Rudik, A., Rivkin, A., Revach, O.-Y., Nir, N., Block Tamin, T., Abou Karam, P., Kiper, E., Peleg, Y., Nevo, R., Solomon, A., Havkin-Solomon, T., Rojas, A., Rotkopf, R., Porat, Z., Avni, D., Schwartz, E., … Regev-Rudzki, N. (2021). Malaria parasites both repress host CXCL10 and use it as a cue for growth acceleration. Nature Communications, 12(1), 4851. https://doi.org/10.1038/s41467-021-24997-7 Cite
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