myeloid cells

[PLoS Biology] Scientists found that interleukin (IL)-25 signaling through its cognate receptor, IL-17 receptor B, increased in adipose tissue after cold exposure and β3-adrenoceptor agonist stimulation.

[Nature Communications] Investigators generated sensorimotor organoids containing physiologically functional neuromuscular junctions and applied the model to different subgroups of amyotrophic lateral sclerosis.

[Scientific Reports] Loss of Cdx function led to a rapid and pronounced attenuation of H2-T3, followed by a decrease in iCD8α cell number, an increase in macrophage infiltration and activation of pro-inflammatory cascades, suggesting a previously unrecognized role for Cdx in intestinal homeostasis through H2-T3-dependent regulation of iCD8α cells.

[Nature Reviews Neurology] The authors focus on the emerging human evidence for an association between maternal immune activation and childhood neurodevelopmental disorders, including autism spectrum disorder, attention-deficit/hyperactivity disorder and Tourette syndrome.

[Scientific Reports] The authors studied the interaction of murine macrophages and intestinal epithelial cells with well-characterized poly(styrene) microplastic particles (MPP) of varying sizes and found that the epithelial cells did not ingest MPP in significant numbers.

[Nature Communications] The authors demonstrated that mice lacking the hypoxia-inducible factor-1α isoform in natural killer (NK) cells showed impaired release of the cytokines Interferon (IFN)-γ and granulocyte macrophage - colony stimulating factor as part of a blunted immune response.