NK Cells in Hypoxic Skin Mediate a Trade-Off between Wound Healing and Antibacterial Defence

The authors demonstrated that mice lacking the hypoxia-inducible factor-1α isoform in natural killer (NK) cells showed impaired release of the cytokines Interferon (IFN)-γ and granulocyte macrophage – colony stimulating factor as part of a blunted immune response.