Tag results:
myeloid cells
Human Immunology News
Neutrophils in Cancer: Heterogeneous and Multifaceted
[Nature Reviews Immunology] Scientists describe how neutrophil diversification, which in some contexts can lead to opposing functions, is generated within the tumour microenvironment as well as systemically.
Mesenchymal Cell News
M1 Macrophage-Derived Exosomes Transfer miR-222 to Induce Bone Marrow Mesenchymal Stem Cell Apoptosis
[Laboratory Investigation] The authors investigated the role of hypoxia/serum deprivation-induced M1-type macrophage-derived exosomes on bone marrow MSC viability, migration, and apoptosis.
Dermal Cell News
The RNase MCPIP3 Promotes Skin Inflammation by Orchestrating Myeloid Cytokine Response
[Nature Communications] Researchers reported that monocyte chemotactic protein-induced protein 3, promoted skin inflammation by simultaneously enhancing tumor necrosis factor in macrophages and repressing interleukin-6 in plasmacytoid dendritic cells.
Umbilical & Placental Cell News
Single-Cell Chromatin Accessibility Landscape of Human Umbilical Cord Blood in Trisomy 18 Syndrome
[Human Genomics] Scientists used the commercial Chromium platform to perform sc-ATAC-seq to measure chromatin accessibility in 11,611 single umbilical cord blood cells derived from one trisomy 18 syndrome patient and one healthy donor.
Cell Therapy News
Hypoproliferative Human Neural Progenitor Cell Xenografts Survived Extendedly in the Brain of Immunocompetent Rats
[Stem Cell Research & Therapy] Neuron-restricted neural progenitor cells (NPCs) were derived from human embryonic stem cells, propagated for different passages, and then transplanted into the brain of immunocompetent rats without immunosuppressants.
Immune Regulation News
Inhibition of EZH2 Prevents Acute Respiratory Distress Syndrome (ARDS)-Associated Pulmonary Fibrosis by Regulating the Macrophage Polarization Phenotype
[Respiratory Research] The authors investigated the role and mechanisms of enhancer of zeste homolog 2 (EZH2) in pulmonary fibrosis in a murine model of LPS-induced acute respiratory distress syndrome (ARDS) and in ex vivo cultured alveolar macrophages and mouse lung epithelial cell line by using 3-deazaneplanocin and EZH2 the small interfering RNA.