NF-κB

[Experimental Eye Research] Researchers generated a diabetic retinopathy (DR) animal model using mice and a cell model in mouse retinal microvascular endothelial cells to examine the role of Trefoil factor family 1 in DR.

[Circulation] Investigators utilized mouse models of reperfused myocardial infarction, angiotensin II and phenylephrine infusion, and diphtheria toxin cardiomyocyte ablation to investigate C-C chemokine ligand 17.

[Science Translational Medicine] Investigators found that distant metastases were more immune inert with increased M2 macrophages compared to their matched primary tumors.

[Chemico-Biological interactions] Scientists discuss the medical value of nutraceuticals briefly and their ability to mitigate various inflammatory lung diseases through targeting inhibition of NF-κB.

[Scientific Reports] The authors suggested that transcriptomic profiling could provide novel information source for studying the neuropathogenesis of enterovirus-A71 infection leading to development of an effective therapeutic measure for central nervous system complications.

[Oxidative Medicine and Cellular Longevity] Researchers investigated the role of flagellin in promoting immunotherapy efficacy through modulating oxidative stress in regulatory B cells.