Tag results:

obesity

FTO Promotes Bortezomib Resistance via m6A-Dependent Destabilization of SOD2 Expression in Multiple Myeloma

[Cancer Gene Therapy] Researchers studied the function and mechanism of Fat mass and obesity associated (FTO) on the Bort resistance of multiple myeloma.

BioRestorative Therapies Announces It Has Initiated Its Phase II Clinical Trial to Treat Chronic Lumbar Disc Disease – Site Selection Underway

[BioRestorative Therapies, Inc. (Globe Newswire, Inc.)] BioRestorative Therapies, Inc. announced that it has initiated the site selection process for its active Phase II clinical trial targeting chronic lumbar disc disease with BRTX-100, a product formulated from autologous cultured MSCs collected from the patient’s bone marrow.

New and Emerging Conditions of Acquired Cutaneous Mucinoses in Adults

[Journal of the European Academy of Dermatology and Venereology] The authors provide an update of what has currently been reported in the last 30-year literature about several new or emerging conditions of acquired cutaneous mucinoses in adults.

Screening for Anti-Adipogenic, Pro-Lipolytic and Thermogenic Plant Extracts by Models Associating Intestinal Epithelial Cells with Human Adipose Cells

[European Journal of Nutrition] Investigators screened the actions of botanical extracts intended for oral use on human adipose tissue, using an in vitro screening model combining human intestinal cells with human adipose cells.

Synthetic Adiponectin-Receptor Agonist, AdipoRon, Induces Glycolytic Dependence in Pancreatic Cancer Cells

[Cell Death & Disease] Treatment of PDAC cells with AdipoRon led to mitochondrial uncoupling and loss of ATP production. Concomitantly, AdipoRon-treated cells increased glucose uptake and utilization.

Suppressive Effects of the Obese Tumor Microenvironment on CD8 T Cell Infiltration and Effector Function

[Journal of Experimental Medicine] The authors investigated the effects of obesity on CD8 T cells in mouse models and patients with endometrial cancer.

Popular