regulatory T cells

[Oncogene] Researchers investigated the role of the NFE2L3 transcription factor in inflammation-induced colorectal cancer.

[Scandinavian Journal of Immunology] The authors analyzed the influence of its precursor 25-hydroxyvitamin D3 on the differentiation of human CD4+ T cells applying physiological concentrations in vitro.

[Cancer Discovery] Researchers interrogated gene expression and whole-genome CRISPR/Cas9 screening in a large panel of patient-derived glioblastoma (GBM) stem cells (GSCs), differentiated GBM cells, and neural stem cells to identify master regulators of GSC stemness.

[Trends in Immunology] The authors detail the novel cellular sensors that are dependent on K63 ubiquitination for their function in the immune signaling network.

[Cell Reports Methods] Scientists showed that fibroblastic, hepatic, or neural tumors were all efficiently infiltrated and partially or totally rejected by autologous immune cells in humanized mice.

[Science Immunology] Investigators applied chromatin conformation capture with immunoprecipitation in Treg and closely related conventional CD4+ T cells.