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squamous cell carcinoma

Decellularized Extracellular Matrix Composite Hydrogel Bioinks for the Development of 3D Bioprinted Head and Neck In Vitro Tumor Models

[ACS Biomaterials Science & Engineering] To overcome the limitation characteristic of pure ECM hydrogels, researchers presented a composite material containing alginate, a seaweed-derived polysaccharide, and gelatin, denatured collagen, as rheological modifiers which imparted mechanical integrity to the biologically active decellularized ECM

C-FOS Drives Reversible Basal to Squamous Cell Carcinoma Transition

[Cell Reports] Researchers used surface markers of resistant basal cell carcinomas and patient single-cell and bulk transcriptomic data, and uncovered the dynamic roadmap of basal to squamous cell carcinoma transition.

DCLK1-Short Splice Variant Promotes Esophageal Squamous Cell Carcinoma Progression Via the MAPK/ERK/MMP2 Pathway

[Molecular Cancer Research] Researchers found that the expression of DCLK1 isoform 4 (DCLK1-S) was significantly increased in human esophageal squamous cell carcinoma tissues and associated with malignant progression and poor prognosis.

SEC61G Overexpression and DNA Amplification Correlates with Prognosis and Immune Cell Infiltration in Head and Neck Squamous Cell Carcinoma

[Cancer Medicine] SEC61G expression was analyzed using publicly available datasets. The association between SEC61G and disease prognosis was evaluated.

The Anti-Tumor Effect of Induced Pluripotent Stem Cells against Submandibular Gland Carcinoma in Rats Is Achieved via Modulation of the Apoptotic Response and the...

[Molecular and Cellular Biochemistry] The authors investigated the contribution of the Bax, Sirt-1, TGF-β, and MALAT genes and/or their protein expression to the pathogenesis of submandibular carcinogenesis before and after iPSCs treatment.

FLT3L Release by NK Cells Enhances Response to Radioimmunotherapy in Preclinical Models of HNSCC

[Clinical Cancer Research] Investigators combined radiation, immunotherapies, genetic mouse models, and antibody depletion experiments to identify the role of NK cells in overcoming resistance to radiation therapy in orthotopic models of head and neck squamous cell carcinoma

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