stem cell markers

[Cellular and Molecular Gastroenterology and Hepatology] Investigators analyzed Lgr5-Cre; APCmin; HER2V777LTg mice by morphologic and gene expression assays on intestinal sections and organoids derived from the epithelium.

[BMC Cancer] Pancreatic ductal adenocarcinoma patients who underwent surgical resection between 01/2012–06/2014 were identified. CD44 and epithelial-specific antigen expression was assessed by immunohistochemistry.

[Cell Death & Disease] Loss of PTEN in fallopian tube epithelium led to the enrichment of CSC markers such as LGR5, WNT4, ALDH1, CD44.

[Cell Host & Microbe] The Scientists assessed the function of skin bacteria in wound healing and wound-induced hair follicle neogenesis (WIHN), a rare adult organogenesis model.

[American Journal of Physiology-Cell Physiology] Colonoid and enteroid gene expression signatures were more similar to those found for the tissues of their origin than to each other.

[Oncogene] Investigators demonstrated how cyclin-dependent kinase 8 (CDK8) played an essential role in maintaining stemness and tumorigenicity in glioma stem cells.