Review

[Stem Cell Research & Therapy] The authors describe the functions of HSCs, analyze the regulatory mechanisms that affect their resting state, and discuss the relationship between resting HSCs and different diseases, with a view to providing guidance for the future clinical implementation of related targeted treatments.

[Journal of Leukocyte Biology] Investigators discuss in detail cell-to-cell interactions in the two leukemic niches, more explored bone marrow and less studied extramedullary adipose tissue.

[Life Sciences] There still exists a gap in the early phase of Rheumatoid arthritis pathogenesis, i.e., the progression of diseases from the systemic circulation to joints. The lack of better understanding of these events results in the inability to answer questions about why only after a certain point of time the disease appears in joints and why in some cases, it simply remains latent and doesn't affect joints at all.

[Current Stem Cell Research & Therapy] The findings of this systematic review support the potential application of the specific miRNAs to regulate the directed differentiation of hDP-MSCs in the field of regenerative therapies.

[Cell Reports] Investigators discuss their applications in studies of regulatory mechanisms involved in early developmental processes, including identification of molecular features, X chromosome inactivation modeling, transposable elements regulation, metabolic characteristics, and cell fate regulation.

[Trends In Molecular Medicine] The authors summarize the evidence that not only multiple cancer cell types, but also cells constituting the tumor microenvironment ‘speak the Wnt language’.