The authors report that ibuprofen diminished cancer cell stemness properties that include reducing the ALDH+ subpopulation, side population and sphere formation in three cancer types.
[British Journal of Cancer]
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Shen, W., Zhang, X., Du, R., Gao, W., Wang, J., Bao, Y., Yang, W., Luo, N., & Li, J. (2020). Ibuprofen mediates histone modification to diminish cancer cell stemness properties via a COX2-dependent manner. British Journal of Cancer, 1–12. https://doi.org/10.1038/s41416-020-0906-7 Cite