MDL-800, An Allosteric Activator of SIRT6, Suppresses Proliferation and Enhances EGFR-TKIs Therapy in Non-Small Cell Lung Cancer

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Scientists investigated whether MDL-800, an allosteric activator of Sirtuin 6, exerted antiproliferation effect against non-small cell lung carcinoma cells in vitro and in vivo.
[Acta Pharmacologica Sinica]
Abstract