The authors showed that either the oral liquid of Shuanghuanglian, the lyophilized powder of Shuanghuanglian for injection or their bioactive components dose-dependently inhibited SARS-CoV-2 3CLpro as well as the replication of SARS-CoV-2 in Vero E6 cells.
[Acta Pharmacologica Sinica]
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Su, H., Yao, S., Zhao, W., Li, M., Liu, J., Shang, W., Xie, H., Ke, C., Hu, H., Gao, M., Yu, K., Liu, H., Shen, J., Tang, W., Zhang, L., Xiao, G., Ni, L., Wang, D., Zuo, J., … Xu, Y. (2020). Anti-SARS-CoV-2 activities in vitro of Shuanghuanglian preparations and bioactive ingredients. Acta Pharmacologica Sinica, 1–11. https://doi.org/10.1038/s41401-020-0483-6 Cite