WNT–β-catenin signaling is involved in chronic kidney disease-associated vascular calcification and mineral bone disease. The WNT–β-catenin pathway is tightly regulated, for example, by proteins of the Dickkopf family.
[Nature Reviews Nephrology]
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Schunk, S. J., Floege, J., Fliser, D., & Speer, T. (2020). WNT–β-catenin signalling — a versatile player in kidney injury and repair. Nature Reviews Nephrology, 1–13. https://doi.org/10.1038/s41581-020-00343-w Cite