Researchers developed mRNA-based JAK-STAT signaling pathway activity assays to quantitatively measure the cellular immune response on Affymetrix expression microarray data of various types of blood samples from virally infected patients, or vaccinated individuals, and to determine vaccine immunogenicity.
[Frontiers in Immunology]
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Bouwman, W., Verhaegh, W., Holtzer, L., & van de Stolpe, A. (2020). Measurement of Cellular Immune Response to Viral Infection and Vaccination. Frontiers in Immunology, 11. https://doi.org/10.3389/fimmu.2020.575074 Cite