To determine the intracellular mechanisms involved in the cardiac effects of oxidized low-density lipoprotein (oxLDL), the authors analyzed the in vitro effect of oxLDL on intracellular Ca2+ handling in adult rat ventricular cardiomyocytes using confocal microscopy.
[Antioxidants]
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Rodríguez-Sánchez, E., Navarro-García, J. A., González-Lafuente, L., Aceves-Ripoll, J., Vázquez-Sánchez, S., Poveda, J., Mercado-García, E., Corbacho-Alonso, N., Calvo-Bonacho, E., Fernández-Velasco, M., Álvarez-Llamas, G., Barderas, M. G., Ruilope, L. M., & Ruiz-Hurtado, G. (2020). Oxidized Low-Density Lipoprotein Associates with Ventricular Stress in Young Adults and Triggers Intracellular Ca2+ Alterations in Adult Ventricular Cardiomyocytes. Antioxidants, 9(12), 1213. https://doi.org/10.3390/antiox9121213 Cite