Local Immune Response to Food Antigens Drives Meal-Induced Abdominal Pain

By
Justin.choi
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Scientists showed that a bacterial infection and bacterial toxins could trigger an immune response that led to the production of dietary-antigen-specific IgE antibodies in mice, which were limited to the intestine.
[Nature]
Aguilera-Lizarraga, J., Florens, M. V., Viola, M. F., Jain, P., Decraecker, L., Appeltans, I., Cuende-Estevez, M., Fabre, N., Van Beek, K., Perna, E., Balemans, D., Stakenborg, N., Theofanous, S., Bosmans, G., Mondelaers, S. U., Matteoli, G., Ibiza Martínez, S., Lopez-Lopez, C., Jaramillo-Polanco, J., … Boeckxstaens, G. E. (2021). Local immune response to food antigens drives meal-induced abdominal pain. Nature, 1–6. https://doi.org/10.1038/s41586-020-03118-2 Cite
Abstract