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Pulmonary Cell NewsThe authors evaluated the potential for a monoclonal antibody antagonist of the glucagon receptor to maintain glucose homeostasis in type 1 diabetic rodents.
[Proceedings of the National Academy of Sciences of the United States of America]
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Wang, M.-Y., Dean, E. D., Quittner-Strom, E., Zhu, Y., Chowdhury, K. H., Zhang, Z., Zhao, S., Li, N., Ye, R., Lee, Y., Zhang, Y., Chen, S., Yu, X., Leonard, D. C., Poffenberger, G., Deylen, A. V., McCorkle, S. K., Schlegel, A., Sloop, K. W., … Holland, W. L. (2021). Glucagon blockade restores functional β-cell mass in type 1 diabetic mice and enhances function of human islets. Proceedings of the National Academy of Sciences, 118(9). https://doi.org/10.1073/pnas.2022142118 Cite
