Fndc5 Knockdown Significantly Decreased the Expression of Neurotrophins and Their Respective Receptors during Neural Differentiation of Mouse Embryonic Stem Cells

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Considering the fact that neurotrophins and their receptors play crucial roles in neural differentiation of ESCs, investigators sought to evaluate whether knockdown of Fndc5 decreased neural differentiation of mESCs by affecting the neurotrophins and their receptors expression.
[Human Cell]
Ebadi, R., Rabiee, F., Kordi-Tamandani, D., Nasr-Esfahani, M. H., & Ghaedi, K. (2021). Fndc5 knockdown significantly decreased the expression of neurotrophins and their respective receptors during neural differentiation of mouse embryonic stem cells. Human Cell. https://doi.org/10.1007/s13577-021-00517-z Cite
Abstract