PEDF Inhibits Lymphatic Metastasis of Nasopharyngeal Carcinoma as a New Lymphangiogenesis Inhibitor

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Mechanistically, pigment epithelium-derived factor (PEDF) inhibited the proliferation, migration, and tube formation of lymphatic endothelial cells and promotes cell apoptosis.
[Cell Death & Disease]
Luo, C., Yin, H., Gao, T., Ma, C., Liu, J., Zhang, T., Xu, Z., Wang, X., Zhang, D., Qi, W., Yang, Z., Gao, G., Yang, X., & Zhou, T. (2021). PEDF inhibits lymphatic metastasis of nasopharyngeal carcinoma as a new lymphangiogenesis inhibitor. Cell Death & Disease, 12(4), 1–14. https://doi.org/10.1038/s41419-021-03583-1 Cite
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