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Pulmonary Cell NewsResearchers showed that genetic or pharmacological inhibition of eukaryotic elongation factor-2 kinase (eEF2K) cooperated with glutamine starvation, and synergized with glutaminase inhibitors to suppress growth of diverse TNBC cell lines.
[Scientific Reports]
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Ju, Y., Ben-David, Y., Rotin, D., & Zacksenhaus, E. (2021). Inhibition of eEF2K synergizes with glutaminase inhibitors or 4EBP1 depletion to suppress growth of triple-negative breast cancer cells. Scientific Reports, 11(1), 9181. https://doi.org/10.1038/s41598-021-88816-1 Cite
