Cyclic AMP-Dependent Activation of ERK via GLP-1 Receptor Signaling Requires the Neuroendocrine Cell-Specific Guanine Nucleotide Exchanger NCS-RapGEF2

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Scientists examined the expression of other Family B Gs‐protein coupled receptor in the cell line and assessed cAMP elevation and neuritogenesis after treatment with their cognate peptide ligands.
[Journal of Neuroendocrinology]
Xu, W., Dahlke, S. P., Emery, A. C., Sung, M., Chepurny, O. G., Holz, G. G., & Eiden, L. E. (n.d.). Cyclic AMP-dependent activation of ERK via GLP-1 receptor signalling requires the neuroendocrine cell-specific guanine nucleotide exchanger NCS-RapGEF2. Journal of Neuroendocrinology, n/a(n/a), e12974. https://doi.org/https://doi.org/10.1111/jne.12974 Cite
Abstract