Phenylethynylbenzyl-Modified Biguanides Inhibit Pancreatic Cancer Tumor Growth

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Scientists presented the design and synthesis of a small library of substituted biguanidium salts and their capacity to inhibit the growth of pancreatic cancer cells.
[Scientific Reports]
Hébert, A., Parisotto, M., Rowell, M.-C., Doré, A., Fernandez Ruiz, A., Lefrançois, G., Kalegari, P., Ferbeyre, G., & Schmitzer, A. R. (2021). Phenylethynylbenzyl-modified biguanides inhibit pancreatic cancer tumor growth. Scientific Reports, 11(1), 9854. https://doi.org/10.1038/s41598-021-87993-3 Cite
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