Pharmacological Inhibition of MDA-9/Syntenin Blocks Breast Cancer Metastasis through Suppression of IL-1β

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Genetic silencing of MDA-9/Syntenin or treatment with a pharmacological inhibitor of the PDZ1 domain, PDZ1i, activated the immune system to kill cancer cells.
[Proceedings of the National Academy of Sciences of the United States of America]

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Abstract