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Pulmonary Cell NewsResearchers observed that early Human rhinoviruses (HRV)-C15 infection induced a transitory barrier-protective metabolic state characterized by glycolysis that ultimately became exhausted as the infection progresses and led to cellular damage.
[Nature Communications]
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Michi, A. N., Yipp, B. G., Dufour, A., Lopes, F., & Proud, D. (2021). PGC-1α mediates a metabolic host defense response in human airway epithelium during rhinovirus infections. Nature Communications, 12(1), 3669. https://doi.org/10.1038/s41467-021-23925-z Cite
