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Pulmonary Cell NewsResearchers investigated the effects of bile acids on tissue factor activity and thrombin generation in hepatocytes and correlated these effects with activation of farnesoid X receptor-dependent signaling and apoptosis.
[Laboratory Investigation]
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Greimel, T., Jahnel, J., Pohl, S., Strini, T., Tischitz, M., Meier-Allard, N., Holasek, S., Meinel, K., Aguiriano-Moser, V., Zobel, J., Haidl, H., Gallistl, S., Panzitt, K., Wagner, M., & Schlagenhauf, A. (2021). Bile acid-induced tissue factor activity in hepatocytes correlates with activation of farnesoid X receptor. Laboratory Investigation, 1–9. https://doi.org/10.1038/s41374-021-00628-z Cite
