LINC00842 Inactivates Transcription Co-regulator PGC-1α to Promote Pancreatic Cancer Malignancy through Metabolic Remodelling

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Justin.choi
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LINC00842 expression was upregulated in pancreatic ductal adenocarcinoma and induced by high concentration of glucose via transcription factor YY1.
[Nature Communications]
Huang, X., Pan, L., Zuo, Z., Li, M., Zeng, L., Li, R., Ye, Y., Zhang, J., Wu, G., Bai, R., Zhuang, L., Wei, L., Zheng, Y., Su, J., Deng, J., Deng, S., Zhang, S., Zhu, S., Che, X., … Zheng, J. (2021). LINC00842 inactivates transcription co-regulator PGC-1α to promote pancreatic cancer malignancy through metabolic remodelling. Nature Communications, 12(1), 3830. https://doi.org/10.1038/s41467-021-23904-4 Cite
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