Scientists established a procedure for placental HSC transplantation into E11.5 Runx1-deficient mice mated with G1-HRD-Runx1 transgenic mice that had no HSCs in the fetal liver.
[Scientific Reports]
Jeon, H., Asano, K., Wakimoto, A., Kulathunga, K., Tran, M. T. N., Nakamura, M., Yokomizo, T., Hamada, M., & Takahashi, S. (2021). Generation of reconstituted hemato-lymphoid murine embryos by placental transplantation into embryos lacking HSCs. Scientific Reports, 11(1), 4374. https://doi.org/10.1038/s41598-021-83652-9 Cite
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