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Pulmonary Cell NewsResearchers developed and applied such assays to measure the levels of leucine-rich repeat kinase 2 as well as the phosphorylation of LRRK2 itself or one of its substrates, Rab10.
[Scientific Reports]
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Wang, X., Negrou, E., Maloney, M. T., Bondar, V. V., Andrews, S. V., Montalban, M., Llapashtica, C., Maciuca, R., Nguyen, H., Solanoy, H., Arguello, A., Przybyla, L., Moerke, N. J., Huntwork-Rodriguez, S., & Henry, A. G. (2021). Understanding LRRK2 kinase activity in preclinical models and human subjects through quantitative analysis of LRRK2 and pT73 Rab10. Scientific Reports, 11(1), 12900. https://doi.org/10.1038/s41598-021-91943-4 Cite
