Differences in In Vitro Microglial Accumulation of the Energy Metabolism Tracers [¹⁸F]FDG and [¹⁸F]BCPP-EF during LPS- and IL4 Stimulation

Scientists evaluated lipopolysaccharide (LPS)- and interleukin 4 (IL4)-stimulated microglial uptake of [¹⁴C]2DG and [¹⁸F]BCPP-EF to give a new insight into the hypothesis that different uptake of [¹⁸F]FDG and [¹⁸F]BCPP-EF could be ascribed to the different metabolic pathways activated during microglial activation.