Diagnostic Potential of Serum Extracellular Vesicles Expressing Prostate-Specific Membrane Antigen in Urologic Malignancies

Investigators developed a sandwich ELISA to detect prostate-specific membrane antigen on small extracellular vesicles (EVs) using T-cell immunoglobulin domain and mucin domain-containing protein 4 as a capture molecule for EVs and to evaluate its diagnostic potential in urologic malignancies.