Toxic Effects of Fluoride in Intestinal Epithelial Cells and the Mitigating Effect of Methanol Extract of Coconut Haustorium by Enhancing De Novo Glutathione Biosynthesis

The possible use of an emerging functional food-the coconut haustorium was evaluated against sodium fluoride-induced toxicity in intestinal cells. The cells exposed to fluoride showed significant cell death mediated through the increased lipid peroxidation and glutathione depletion.