Induction and Expansion of Human PRRX1+ Limb-Bud-Like Mesenchymal Cells from Pluripotent Stem Cells

Scientists reported a protocol that leveraged PRRX1–tdTomato reporter human PSCs for the selective induction of expandable and ontogenetically defined PRRX1+ limb-bud-like mesenchymal cells under defined xeno-free conditions.