Triple-Negative Breast Cancer: Understanding Wnt Signaling in Drug Resistance

Investigators summarize mechanisms of Wnt/β-catenin signaling for resistance development in TNBC, the complex interaction between Wnt/β-catenin signaling, and the transactivated receptor tyrosine kinase signaling pathways, lymphocytic infiltration, epithelial-mesenchymal transition, and induction of metastasis.