Deafness-in-a-Dish: Modeling Hereditary Deafness with Inner Ear Organoids

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Investigators discuss the advantages and limitations of conventional models of the human auditory system, describe the generation and characteristics of PSC-derived inner ear organoids, and discuss several strategies and recent attempts to model hereditary deafness in vitro.
[Human Genetics]
Romano, D. R., Hashino, E., & Nelson, R. F. (2021). Deafness-in-a-dish: modeling hereditary deafness with inner ear organoids. Human Genetics. https://doi.org/10.1007/s00439-021-02325-9 Cite
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