Researchers analyzed the permissiveness of primary endothelial cells of the human pulmonary microvasculature and of primary human epithelial cells derived from bronchi, bronchioles and alveoli for Old World orthohantavirus Puumala virus in vitro.
[Virology Journal]
6445218 W76YBYAW items 1 apa 0 default asc 1 165899 https://www.stemcellsciencenews.com/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3A%22zotpress-bc0fe3e10fc02604cb69ce6017fef642%22%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22W76YBYAW%22%2C%22library%22%3A%7B%22id%22%3A6445218%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22H%5Cu00e4gele%20et%20al.%22%2C%22parsedDate%22%3A%222021-08-17%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EH%26%23xE4%3Bgele%2C%20S.%2C%20Nusshag%2C%20C.%2C%20M%26%23xFC%3Bller%2C%20A.%2C%20Baumann%2C%20A.%2C%20Zeier%2C%20M.%2C%20%26amp%3B%20Krautkr%26%23xE4%3Bmer%2C%20E.%20%282021%29.%20Cells%20of%20the%20human%20respiratory%20tract%20support%20the%20replication%20of%20pathogenic%20Old%20World%20orthohantavirus%20Puumala.%20%3Ci%3EVirology%20Journal%3C%5C%2Fi%3E%2C%20%3Ci%3E18%3C%5C%2Fi%3E%281%29%2C%20169.%20%3Ca%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12985-021-01636-7%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12985-021-01636-7%3C%5C%2Fa%3E%20%3Ca%20title%3D%27Cite%20in%20RIS%20Format%27%20class%3D%27zp-CiteRIS%27%20href%3D%27https%3A%5C%2F%5C%2Fwww.stemcellsciencenews.com%5C%2Fwp-content%5C%2Fplugins%5C%2Fzotpress%5C%2Flib%5C%2Frequest%5C%2Frequest.cite.php%3Fapi_user_id%3D6445218%26amp%3Bitem_key%3DW76YBYAW%27%3ECite%3C%5C%2Fa%3E%20%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Cells%20of%20the%20human%20respiratory%20tract%20support%20the%20replication%20of%20pathogenic%20Old%20World%20orthohantavirus%20Puumala%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stefan%22%2C%22lastName%22%3A%22H%5Cu00e4gele%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%22%2C%22lastName%22%3A%22Nusshag%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alexander%22%2C%22lastName%22%3A%22M%5Cu00fcller%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alexandra%22%2C%22lastName%22%3A%22Baumann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Martin%22%2C%22lastName%22%3A%22Zeier%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ellen%22%2C%22lastName%22%3A%22Krautkr%5Cu00e4mer%22%7D%5D%2C%22abstractNote%22%3A%22Transmission%20of%20all%20known%20pathogenic%20orthohantaviruses%20%28family%20Hantaviridae%29%20usually%20occurs%20via%20inhalation%20of%20aerosols%20contaminated%20with%20viral%20particles%20derived%20from%20infected%20rodents%20and%20organ%20manifestation%20of%20infections%20is%20characterized%20by%20lung%20and%20kidney%20involvement.%20Orthohantaviruses%20found%20in%20Eurasia%20cause%20hemorrhagic%20fever%20with%20renal%20syndrome%20%28HFRS%29%20and%20New%20World%20orthohantaviruses%20cause%20hantavirus%20cardiopulmonary%20syndrome%20%28HCPS%29.%20However%2C%20cases%20of%20infection%20with%20Old%20World%20orthohantaviruses%20with%20severe%20pulmonary%20manifestations%20have%20also%20been%20observed.%20Therefore%2C%20human%20airway%20cells%20may%20represent%20initial%20targets%20for%20orthohantavirus%20infection%20and%20may%20also%20play%20a%20role%20in%20the%20pathogenesis%20of%20infections%20with%20Eurasian%20orthohantaviruses.%22%2C%22date%22%3A%22August%2017%2C%202021%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1186%5C%2Fs12985-021-01636-7%22%2C%22ISSN%22%3A%221743-422X%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12985-021-01636-7%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222021-08-18T22%3A30%3A03Z%22%7D%7D%5D%7D
Hägele, S., Nusshag, C., Müller, A., Baumann, A., Zeier, M., & Krautkrämer, E. (2021). Cells of the human respiratory tract support the replication of pathogenic Old World orthohantavirus Puumala. Virology Journal, 18(1), 169. https://doi.org/10.1186/s12985-021-01636-7 Cite