Single-Cell Imaging of T Cell Immunotherapy Responses In Vivo

By
Justin.choi
-
0
21
Optically clear immunocompromised zebrafish were engrafted with fluorescent-labeled human cancers along with CAR T cells, bispecific T cell engagers, and antibody peptide epitope conjugates, allowing real-time single-cell visualization of T cell–based immunotherapies in vivo.
[Journal of Experimental Medicine]
Yan, C., Yang, Q., Zhang, S., Millar, D. G., Alpert, E. J., Do, D., Veloso, A., Brunson, D. C., Drapkin, B. J., Stanzione, M., Scarfò, I., Moore, J. C., Iyer, S., Qin, Q., Wei, Y., McCarthy, K. M., Rawls, J. F., Dyson, N. J., Cobbold, M., … Langenau, D. M. (2021). Single-cell imaging of T cell immunotherapy responses in vivo. Journal of Experimental Medicine, 218(10). https://doi.org/10.1084/jem.20210314 Cite
Full Article