Therapeutic Inhibition of USP9x-Mediated Notch Signaling in Triple-Negative Breast Cancer

By
Justin.choi
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0
6
Using a murine TNBC model, scientists showed that USP9x knockdown abrogated Notch activation, reducing the production of the proinflammatory cytokines, C-C motif chemokine ligand 2 and interleukin-1 beta.
[Proceedings of the National Academy of Sciences of the United States of America]
Abstract