Kinectin1 Depletion Promotes EGFR Degradation via the Ubiquitin-Proteosome System in Cutaneous Squamous Cell Carcinoma

Researchers demonstrated that kinectin1 knockdown induced epidermal growth factor receptor (EGFR) degradation in cutaneous squamous cell carcinoma cells and promoted the ubiquitin-proteasome system, and that this effect was tumor cell-specific.