YEATS2 Regulates the Activation of TAK1/NF-κB Pathway and Is Critical for Pancreatic Ductal Adenocarcinoma Cell Survival

Constitutive activation of NF-κB is frequently observed in pancreatic ductal adenocarcinoma (PDAC). Scientists found that YEATS2, a scaffolding protein of ATAC complex, was highly expressed in human PDAC.