Delayed Fractional Dosing with RTS, S/AS01 Improves Humoral Immunity to Malaria via a Balance of Polyfunctional NANP6- and Pf16-Specific Antibodies

The authors demonstrated that the delayed fractional dose maintained monocyte phagocytosis and NK activation mediated by NANP6-specific antibodies, key correlates of protection for the RTS,S/AS01 doses regimen.