Roles of IκB Kinases and TANK-Binding Kinase 1 in Hepatic Lipid Metabolism and Nonalcoholic Fatty Liver Disease

The authors review the biochemical steps of hepatic lipid metabolism, dysregulated lipid metabolism in obesity and nonalcoholic fatty liver disease (NAFLD), and the roles of IκB kinase complexes and TANK-binding kinase 1 in obesity and NAFLD.