Aberrant Chromatin Landscape Following Loss of the H3.3 Chaperone Daxx in Hematopoietic Precursors Leads to Pu.1-Mediated Neutrophilia and Inflammation

The authors findings implicated retrotransposable element silencing in hematopoiesis and suggested a cross-talk between the H3.3 loading machinery and the pioneer transcription factor Pu.1.