Glioblastoma Stem Cells Reprogram Chromatin In Vivo to Generate Selective Therapeutic Dependencies on DPY30 and Phosphodiesterases

By
Justin.choi
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Scientists identified DPY30, a regulator of histone H3 lysine 4 trimethylation, as a driver of glioblastoma growth in vivo but not in vitro.
[Science Translational Medicine]
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