Boosting NAD⁺ Blunts Toll-Like Receptor-4 Induced Type-I Interferon in Control and Systemic Lupus Erythematosus Monocytes

Scientists explored the underlying biology in myeloid cells from healthy volunteers following in vivo placebo or nicotinamide riboside administration and subsequently tested the findings in vitro in monocytes extracted from subjects with systemic lupus erythematosus.