PD-L1 Mediates Lung Fibroblast to Myofibroblast Transition through Smad3 and β-Catenin Signaling Pathways

Researchers demonstrated that fibroblast programmed death ligand-1 (PD-L1) may have promoted pulmonary fibrosis through both Smad3 and β-catenin signaling and may represent a novel interventional target for idiopathic pulmonary fibrosis.