p53 Reactivating Small Molecule PRIMA-1^MET/APR-246 Regulates Genomic Instability in MDA-MB-231 Cells

Researchers investigated the reactivation of p53 in DNA repair mechanisms and the maintenance of genomic stability using PRIMA‑1METAPR‑246 small molecules, in both MDA‑MB‑231 and MCF‑7 breast cancer cell lines.