Activation of the Notch1-C-Myc-VCAM1 Signaling Axis Initiates Liver Progenitor Cell-Driven Hepatocarcinogenesis and Pulmonary Metastasis

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Researchers discovered that the Notch1-c-myc-VCAM1 signaling axis initiates liver progenitor cell-driven hepatocarcinogenesis and metastasis, providing a preclinical model for HCC study.
[Oncogene]
Abstract